Our Studies

Below are some of our ongoing studies!

Research Overview

The SCAN Lab combines brain imaging, measures of peripheral arousal like heart rate, and behavior to determine atypical sensory processing in different groups of children and adolescents. We particularly focus on sensory over-responsivity (SOR), which is characterized as a heightened, atypical response to some sensory stimuli, affects multiple clinical groups, and can greatly impact how people process their social environment and function in daily life. Our goal is to better understand what causes impairing sensory processing differences, and how they affect other areas of functioning so we can help develop interventions to improve quality of life.
 

Current Studies

Sensory Regulation Development: A Longitudinal Study

PI: Dr. Shulamite Green

Purpose

This longitudinal study aims to examine how sensory reactivity and regulation develops over time in youth with autism compared to typically developing controls. By identifying the neurobioloigcal mechanisms that support sensory regulation development in these groups, we hope to inform the creation of more targetted and effective therapeutic interventions.

We’ve already worked with over 75 children and their families, but we’re still actively recruiting!

Involvement

2-3 visits to UCLA, over the course of about 2 years 

Each study time-point will include:

  • A 1.5 hour brain scan (MRI)
  • Sensory assessments (some including physiological measurements, such as heart rate)
  • Parent/Participant Questionnaires

Benefits

Participants will receive:

  • Up to $270
  • A picture of their brain!
  • Optional research report on their sensory processing

Recruiting

Immediate enrollment opportunities for youth with autism or typically developing controls, ages 8-15!

Contact

  • Please feel free to email us at scanlab@mednet.ucla.edu if you are interested in participating. 
  • You can also text or call ‪(323) 391-8795‬ for more information and to complete a short screening interview (15 minutes).

Sensory Over-Responsivity Across the Spectrum

PI: Dr. Shulamite Green

Purpose

This study aims to examine how sensory reactivity and regulation develops in youth across the autism spectrum.

We will measure your child’s heart rate and sweat levels while they play with different sensory games to understand sensory avoidance in autism.

We are also including participants who have a wider range of verbal and cognitive skills.

Some participants may also be eligible for an MRI scan!

This is a new study, and we will start recruiting participants in the fall of 2024!

Involvement

1-2 visits to UCLA

A study visit will include:

  • Sensory assessments (some including physiological measurements, such as heart rate)
  • Parent/Participant Questionnaires
  • An optional brain scan (if participants are eligible)

Benefits

Participants will receive:

  • Up to $100
  • A picture of their brain (if they complete the brain scan)!

Recruiting

We are recruiting children with autism between the ages 7-15!

We are also including participants with a wider range of verbal and cognitive skills.  

Contact

  • Please feel free to email us at scanlab@mednet.ucla.edu if you are interested in participating. 
  • You can also text or call ‪(323) 391-8795‬ for more information and to complete a short screening interview (15 minutes).

Effect of Propranolol on Neurobiological Mechanisms of Sensory Over-Responsivity

PI: Dr. Shulamite Green

Purpose

We are examining a previously established medication, propranolol, for sensory over-responsivity (SOR). Propranolol, a beta-blocker, is a widely used daily preventative medication for individuals ranging from infants to adolescents/adults, and is used to treat conditions such as headache, stage fright, and tremor.

Currently, intervention for SOR is limited, and there are no medications that have been specifically studied to treat it. This study will help us gain a better understanding of how propranolol affects brain and body responses during sensory processing, which is an important first step to determine if it can treat SOR symptoms. 

We will be recruiting through the summer of 2024 for this study! 

Involvement

3 visits to UCLA

The first study visit will be about an hour long, where our physician will go over the consent form for this study and complete an intake form to determine if your child is eligible. 

The second and third study visits will include:

  • 1 hour MRI scan
  • Sensory assessments (some including physiological measurements, such as heart rate)
  • Parent/Participant Questionnaires

Benefits

Participants will receive:

  • Up to $175
  • A picture of their brain!

Recruiting

We are recruiting children with autism between the ages 8-15!

Contact

  • Please feel free to email us at scanlab@mednet.ucla.edu if you are interested in participating. 
  • You can also text or call ‪(323) 391-8795‬ for more information and to complete a short screening interview (15 minutes).

Transcranial Magnetic Stimulation and Sensory Over-Responsivity (Autistic adults, ages 18-35)

PI: Dr. Shulamite Green

Purpose

This study will examine whether transcranial magnetic stimulation (TMS) can be used to reduce brain responses to aversive sensations in people with autism and sensory over-responsivity (SOR). TMS is a noninvasive brain treatment technique that uses magnetic waves that pass through the skull to stimulate the outer layer of the brain. It is typically used to treat individuals with depression but is being tested as a novel treatment for SOR. Currently, intervention for SOR is limited and this study will help us gain a better understanding of how TMS affects brain responses during sensory processing which is an important first step to determining if it can treat SOR symptoms.

Participation would involve 3 study visits to UCLA. The first visit will last around 1.5- 2 hours and involve a consent session, MRI, and study questionnaires. The following 2 study visits will last around 2-2.5 hours and include an MRI scan and a round of TMS. You will receive $50 for the first study visit, plus $75 for the following 2 visits, for up to $200 in total. We compensate for parking during our visits as well. 

We are finishing up recruitment for this study in the summer of 2024!

Contact

  • Please feel free to email us at scanlab@mednet.ucla.edu if you are interested in participating. 
  • You can also text or call ‪(323) 391-8795‬ for more information and to complete a short screening interview (15 minutes).

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